There are many ways of classifying Gynecomastia.
It could be classified according to which part is enlarged : (1) True Gynecomastia – gland enlargement (2) False Gynecomastia – Over fat accumulation (3) Mixed Type – Both gland & fat overgrowth.
And, It could also be classified according to its time of onset & cause,
– Newborn gynecomastia
- Physiological response to high levels of maternal and placental estrogen transferred in utero. A secretion sometimes called witch’s milk can often be expressed.
– Pubertal gynecomastia:
- Physiological response to the increase in the testosterone-fueled by marked increases in GH, insulin-like growth factor-1, FSH, and LH at puberty
- Estrogen increases 3-fold, but peaks earlier than testosterone.
– Adult gynecomastia (physiological):
- Physiological response to the decrease in free testosterone and the increase in adipose tissue that often accompanies aging
- Testosterone is converted to estrogen in adipose tissue.
– Adult gynecomastia (non-physiological):